Multi-modality IGRT
Our radiotherapy department implements image-guided radiotherapy (IGRT) utilizing cutting-edge technology, including MR-guided radiotherapy and 4DCT, to precisely target tumors while minimizing damage to surrounding healthy tissue. By incorporating advanced imaging techniques before and during treatment sessions, IGRT allows for real-time adjustments to ensure accurate radiation delivery. This state-of-the-art approach enhances treatment efficacy and improves patient outcomes.
A selection of our projects:
This study aimed to develop and validate a comprehensive, reproducible and automatic 4DCT Quality Assurance (QA) workflow (QAMotion) that evaluates image accuracy across various regular and irregular breathing patterns. Volume and amplitude deviations, CT number accuracy, and spatial integrity were used as evaluation metrics. For repeatability tests, tolerances were respected with a mean CT number deviation < 10 HU, volume deviation < 2% and diameter and amplitude deviation < 2 mm except for irregular amplitude curves for which an amplitude deviation up to 6 mm was measured. QAMotion was able to flag image artifacts for our clinical 4DCT system.
A multi-institutional multi-vendor 4DCT audit was conducted to evaluate the accuracy of current imaging protocols in capturing tumor and organ motion over time. Regular breathing patterns showed consistent accuracy across institutions, while irregular patterns exhibited more variability, with deviations in volume, CT number, and amplitude. The study underscores the importance of a standardized 4DCT quality assurance program to ensure consistent and reliable results across different centers.
A working group of ESTRO has been set up to democratize access to dual-energy computed tomography (DECT) in RT departments, and to encourage the creation of the large-scale databases needed to train automatic segmentation algorithms. The study will assess the contribution of DECT to target volume definition, with the aim of reducing inter-observer variability and eliminating the need for additional imaging modalities.
Selected Publications:
Results of a multicenter 4D computed tomography quality assurance audit: Evaluating image accuracy and consistency
M Burghelea, JB Tahiri, J Dhont, et al. Phys Imaging Radiat Oncol, 28; 100479. (2023) DOI: 10.1016/j.phro.2023.100479
A comprehensive quality assurance program for four-dimensional computed tomography in radiotherapy
JB Tahiri, M Kyndt, J Dhont, et al. Phys Imaging Radiat Oncol, 27; 100475. (2023) DOI: 10.1016/j.phro.2023.100475
OC-0111 Results of multi-centric 4DCT QA audit: evaluating the accuracy and consistency of 4D imaging
M Burghelea, JB Tahiri, M Kyndt, et al. Radiother Oncol, 182;S71-S72. (2023)
DOI: 10.1016/S0167-8140(23)08525-0
PD-0581 Development of a comprehensive 4DCT QA program: Implementation and validation
JB Tahiri, M Burghelea, M Kyndt, et al. Radiother Oncol, 182;S462-S464. (2023) DOI: 10.1016/S0167-8140(23)08931-4
A selection of our projects:
- 4DCT QA program
This study aimed to develop and validate a comprehensive, reproducible and automatic 4DCT Quality Assurance (QA) workflow (QAMotion) that evaluates image accuracy across various regular and irregular breathing patterns. Volume and amplitude deviations, CT number accuracy, and spatial integrity were used as evaluation metrics. For repeatability tests, tolerances were respected with a mean CT number deviation < 10 HU, volume deviation < 2% and diameter and amplitude deviation < 2 mm except for irregular amplitude curves for which an amplitude deviation up to 6 mm was measured. QAMotion was able to flag image artifacts for our clinical 4DCT system.
- Multicentric 4DCT QA audit
A multi-institutional multi-vendor 4DCT audit was conducted to evaluate the accuracy of current imaging protocols in capturing tumor and organ motion over time. Regular breathing patterns showed consistent accuracy across institutions, while irregular patterns exhibited more variability, with deviations in volume, CT number, and amplitude. The study underscores the importance of a standardized 4DCT quality assurance program to ensure consistent and reliable results across different centers.
- Dual-energy CT scanner (DECT) for automatic target volume segmentation in radiotherapy of cancers of the H&N sphere
A working group of ESTRO has been set up to democratize access to dual-energy computed tomography (DECT) in RT departments, and to encourage the creation of the large-scale databases needed to train automatic segmentation algorithms. The study will assess the contribution of DECT to target volume definition, with the aim of reducing inter-observer variability and eliminating the need for additional imaging modalities.
Selected Publications:
Results of a multicenter 4D computed tomography quality assurance audit: Evaluating image accuracy and consistency
M Burghelea, JB Tahiri, J Dhont, et al. Phys Imaging Radiat Oncol, 28; 100479. (2023) DOI: 10.1016/j.phro.2023.100479
A comprehensive quality assurance program for four-dimensional computed tomography in radiotherapy
JB Tahiri, M Kyndt, J Dhont, et al. Phys Imaging Radiat Oncol, 27; 100475. (2023) DOI: 10.1016/j.phro.2023.100475
OC-0111 Results of multi-centric 4DCT QA audit: evaluating the accuracy and consistency of 4D imaging
M Burghelea, JB Tahiri, M Kyndt, et al. Radiother Oncol, 182;S71-S72. (2023)
DOI: 10.1016/S0167-8140(23)08525-0
PD-0581 Development of a comprehensive 4DCT QA program: Implementation and validation
JB Tahiri, M Burghelea, M Kyndt, et al. Radiother Oncol, 182;S462-S464. (2023) DOI: 10.1016/S0167-8140(23)08931-4