RESEARCH OUTPUT
Publications 2019-2024
2024
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga.
Moris, V. C., Bruneau, L., Berthe, et al. BMC biology, 22(1), 11. (2024) DOI: 10.1186/s12915-023-01807-8
C. elegans: A potent model for high-throughput screening experiments investigating the FLASH effect.
Schoenauen, L., Stubbe, F. X., Van Gestel, et al. Clinical and translational radiation oncology, 100712 (2024) DOI: 10.1016/j.ctro.2023.100712
[18F]FDG PET/CT-Avid Discordant Volume as a Biomarker in Patients with Gastroenteropancreatic Neuroendocrine Neoplasms: A Multicenter Study.
Chan DL, Hayes AR, Karfis I, Conner A, et al. J Nucl Med. 65(2):185-191. (2024) doi:10.2967/jnumed.
Prediction of 177Lu-DOTATATE PRRT Outcome Using Multimodality Imaging in Patients with Gastroenteropancreatic Neuroendocrine Tumors: Results from a Prospective Phase II LUMEN Study.
Mileva M, Marin G, Levillain H, et al. J Nucl Med. 65(2):236-244. (2024) doi:10.2967/jnumed.123.265987.
2023
Real-time motion management in MRI-guided radiotherapy: Current status and AI-enabled prospects.
E Lombardo, J Dhont, D Page, et al. Radiother Oncol, 109970. (2023) DOI: 10.1016/j.radonc.2023.109970
Results of a multicenter 4D computed tomography quality assurance audit: Evaluating image accuracy and consistency
M Burghelea, JB Tahiri, J Dhont, et al. Phys Imaging Radiat Oncol, 28; 100479. (2023) DOI: 10.1016/j.phro.2023.100479
A comprehensive quality assurance program for four-dimensional computed tomography in radiotherapy
JB Tahiri, M Kyndt, J Dhont, et al. Phys Imaging Radiat Oncol, 27; 100475. (2023) DOI: 10.1016/j.phro.2023.100475
OC-0111 Results of multi-centric 4DCT QA audit: evaluating the accuracy and consistency of 4D imaging
M Burghelea, JB Tahiri, M Kyndt, et al. Radiother Oncol, 182;S71-S72. (2023) DOI: 10.1016/S0167-8140(23)08525-0
PD-0581 Development of a comprehensive 4DCT QA program: Implementation and validation
JB Tahiri, M Burghelea, M Kyndt, et al. Radiother Oncol, 182;S462-S464. (2023) DOI: 10.1016/S0167-8140(23)08931-4
Radiation therapy-activated nanoparticle and immunotherapy: The next milestone in oncology?
Penninckx, S., Thariat, J., & Mirjolet, C. International Review of Cell and Molecular Biology, 378, 157-200 (2023). DOI: 10.1016/bs.ircmb.2023.03.005
Back to the roots, desiccation and radiation resistances are ancestral characters in bdelloid rotifers.
Hespeels, B., Fontaneto, D., Cornet, V., et al. BMC biology, 21(1), 72 (2023). DOI: 10.1186/s12915-023-01554-w
Advances in the Mechanistic Understanding of Iron Oxide Nanoparticles’ Radiosensitizing Properties
Ternad, I., Penninckx, S., Lecomte, V., et al. Nanomaterials, 13(1), 201. (2023). DOI: 10.3390/nano13010201
Radiation-activated nanoparticles: Which combination to optimize radiosensitization?
Penninckx, S., Martinive, P., & Mirjolet, C. Cancer/Radiothérapie, 27(6-7), 494-498. (2023). DOI: 10.1016/j.canrad.2023.07.002
Quantitative 177Lu SPECT/CT imaging for personalized dosimetry using a ring-shaped CZT-based camera.
Danieli R, Stella M, Leube J, et al. EJNMMI Phys. 10(1):64. (2023) doi:10.1186/s40658-023-00586-z.
Clinical impact of 99mTc-MAA SPECT/CT-based personalized predictive dosimetry in selective internal radiotherapy: a real-life single-center experience in unresectable HCC patients.
Bucalau AM, Collette B, Tancredi I, et al. Eur J Hybrid Imaging. 7(1):12. (2023) doi:10.1186/s41824-023-00171-8.
Dual [68Ga]DOTATATE and [18F]FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasms: a multicentre validation of the NETPET score.
Chan DL, Hayes AR, Karfis I, et al. Br J Cancer. 128(4):549-555. (2023) doi:10.1038/s41416-022-02061-5.
2022
Pre-trial quality assurance of diffusion-weighted MRI for radiomic analysis and the role of harmonisation
Z Paquier, SL Chao, G Bregni, et al. Phys Med, 130;138-146. (2022) DOI: 10.1016/j.ejmp.2022.10.009
Radiomics software comparison using digital phantom and patient data: IBSI-compliance does not guarantee concordance of feature values
Z Paquier, SL Chao, A Acquisto, et al. Biomed Phys Eng Express, 8(6). (2022) DOI: 10.1088/2057-1976/ac8e6f
Machine learning model using F-18-FDG PET/CT-based biomarkers to support clinical decision making in advanced chemorefractory metastatic colorectal cancer.
J Dhont, H Levillain, T Guiot, et al. Eur J Nucl Med Mol Imaging, 49(1);S242-243. (2022) DOI: 10.1007/s00259-022-05924-4
Understanding the Radiobiological Mechanisms Induced by 177Lu-DOTATATE in Comparison to External Beam Radiation Therapy
Delbart, W., Karabet, J., Marin, G., et al. Int J of molecular sciences, 23(20), 12369. (2022). DOI: 10.3390/ijms232012369
Mouse genomic associations with in vitro sensitivity to simulated space radiation.
Cekanaviciute, E., Tran, D., Nguyen, H., et al. Life Sciences in Space Research, 36, 47-58. (2022). DOI: 10.1016/j.lssr.2022.07.006
International recommendations for personalized selective internal radiation therapy of primary and metastatic liver diseases with yttrium-90 resin microspheres.
Levillain H, Bagni O, Deroose CM, et al. Eur J Nucl Med Mol Imaging. 48(5):1570-1584. (2021) doi:10.1007/s00259-020-05163-5.
Combined quality and dose-volume histograms for assessing the predictive value of 99mTc-MAA SPECT/CT simulation for personalizing radioembolization treatment in liver metastatic colorectal cancer.
Levillain H, Burghelea M, Derijckere ID, et al. EJNMMI Phys. 7(1):75. (2020) doi: 10.1186/s40658-020-00345-4.
Prognostic value of a three-scale grading system based on combining molecular imaging with 68Ga-DOTATATE and 18F-FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasias.
Karfis I, Marin G, Levillain H, et al. Oncotarget. 11(6):589-599. (2020) doi: 10.18632/oncotarget.27460.
2021
Quantification of radiation-induced DNA double strand break repair foci to evaluate and predict biological responses to ionizing radiation
Penninckx, S., Pariset, E., Cekanaviciute, E., et al. NAR cancer, 3(4), zcab046. (2021). DOI: 10.1093/narcan/zcab046
Metallic Nanoparticles: A Useful Prompt Gamma Emitter for Range Monitoring in Proton Therapy?
Penninckx, S., Hespeels, F., Smeets, J., et al. Radiation, 1(4), 305-316 (2021). DOI: 10.3390/radiation1040025
Considering cell proliferation to optimize detection of radiation-induced 53BP1 positive foci in 15 mouse strains ex vivo
Penninckx, S., Pariset, E., Acuna, A. U., et al. Radiation Research, 195(1), 47-59. (2021). DOI: 10.1667/RADE-20-00165.1
2020
The metabolic clinical risk score as a new prognostic model for surgical decision-making in patients with colorectal liver metastases.
Duran Derijckere I, Levillain H, Bohlok A, et al. J Surg Oncol. 121(2):350-356. (2020) doi: 10.1002/jso.25763.
2019
Personalised radioembolization improves outcomes in refractory intra-hepatic cholangiocarcinoma: a multicenter study.
Levillain H, Duran Derijckere I, Ameye L,et al. Eur J Nucl Med Mol Imaging. 46(11):2270-2279. (2019) doi: 10.1007/s00259-019-04427-z.
2018
Selective internal radiation therapy (SIRT) before partial hepatectomy or radiofrequency destruction for treatment of hepatocellular carcinoma in cirrhotic patients: a feasibility and safety pilot study.
Lemaire M, Lucidi V, Bouazza F, et al. HPB (Oxford). 20(7):641-648. (2018) doi: 10.1016/j.hpb.2018.01.006.
A dosimetry procedure for organs-at-risk in 177Lu peptide receptor radionuclide therapy of patients with neuroendocrine tumours.
Marin G, Vanderlinden B, Karfis I, et al. Phys Med. Dec;56:41-49. (2018) doi: 10.1016/j.ejmp.2018.11.001.
2024
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga.
Moris, V. C., Bruneau, L., Berthe, et al. BMC biology, 22(1), 11. (2024) DOI: 10.1186/s12915-023-01807-8
C. elegans: A potent model for high-throughput screening experiments investigating the FLASH effect.
Schoenauen, L., Stubbe, F. X., Van Gestel, et al. Clinical and translational radiation oncology, 100712 (2024) DOI: 10.1016/j.ctro.2023.100712
[18F]FDG PET/CT-Avid Discordant Volume as a Biomarker in Patients with Gastroenteropancreatic Neuroendocrine Neoplasms: A Multicenter Study.
Chan DL, Hayes AR, Karfis I, Conner A, et al. J Nucl Med. 65(2):185-191. (2024) doi:10.2967/jnumed.
Prediction of 177Lu-DOTATATE PRRT Outcome Using Multimodality Imaging in Patients with Gastroenteropancreatic Neuroendocrine Tumors: Results from a Prospective Phase II LUMEN Study.
Mileva M, Marin G, Levillain H, et al. J Nucl Med. 65(2):236-244. (2024) doi:10.2967/jnumed.123.265987.
2023
Real-time motion management in MRI-guided radiotherapy: Current status and AI-enabled prospects.
E Lombardo, J Dhont, D Page, et al. Radiother Oncol, 109970. (2023) DOI: 10.1016/j.radonc.2023.109970
Results of a multicenter 4D computed tomography quality assurance audit: Evaluating image accuracy and consistency
M Burghelea, JB Tahiri, J Dhont, et al. Phys Imaging Radiat Oncol, 28; 100479. (2023) DOI: 10.1016/j.phro.2023.100479
A comprehensive quality assurance program for four-dimensional computed tomography in radiotherapy
JB Tahiri, M Kyndt, J Dhont, et al. Phys Imaging Radiat Oncol, 27; 100475. (2023) DOI: 10.1016/j.phro.2023.100475
OC-0111 Results of multi-centric 4DCT QA audit: evaluating the accuracy and consistency of 4D imaging
M Burghelea, JB Tahiri, M Kyndt, et al. Radiother Oncol, 182;S71-S72. (2023) DOI: 10.1016/S0167-8140(23)08525-0
PD-0581 Development of a comprehensive 4DCT QA program: Implementation and validation
JB Tahiri, M Burghelea, M Kyndt, et al. Radiother Oncol, 182;S462-S464. (2023) DOI: 10.1016/S0167-8140(23)08931-4
Radiation therapy-activated nanoparticle and immunotherapy: The next milestone in oncology?
Penninckx, S., Thariat, J., & Mirjolet, C. International Review of Cell and Molecular Biology, 378, 157-200 (2023). DOI: 10.1016/bs.ircmb.2023.03.005
Back to the roots, desiccation and radiation resistances are ancestral characters in bdelloid rotifers.
Hespeels, B., Fontaneto, D., Cornet, V., et al. BMC biology, 21(1), 72 (2023). DOI: 10.1186/s12915-023-01554-w
Advances in the Mechanistic Understanding of Iron Oxide Nanoparticles’ Radiosensitizing Properties
Ternad, I., Penninckx, S., Lecomte, V., et al. Nanomaterials, 13(1), 201. (2023). DOI: 10.3390/nano13010201
Radiation-activated nanoparticles: Which combination to optimize radiosensitization?
Penninckx, S., Martinive, P., & Mirjolet, C. Cancer/Radiothérapie, 27(6-7), 494-498. (2023). DOI: 10.1016/j.canrad.2023.07.002
Quantitative 177Lu SPECT/CT imaging for personalized dosimetry using a ring-shaped CZT-based camera.
Danieli R, Stella M, Leube J, et al. EJNMMI Phys. 10(1):64. (2023) doi:10.1186/s40658-023-00586-z.
Clinical impact of 99mTc-MAA SPECT/CT-based personalized predictive dosimetry in selective internal radiotherapy: a real-life single-center experience in unresectable HCC patients.
Bucalau AM, Collette B, Tancredi I, et al. Eur J Hybrid Imaging. 7(1):12. (2023) doi:10.1186/s41824-023-00171-8.
Dual [68Ga]DOTATATE and [18F]FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasms: a multicentre validation of the NETPET score.
Chan DL, Hayes AR, Karfis I, et al. Br J Cancer. 128(4):549-555. (2023) doi:10.1038/s41416-022-02061-5.
2022
Pre-trial quality assurance of diffusion-weighted MRI for radiomic analysis and the role of harmonisation
Z Paquier, SL Chao, G Bregni, et al. Phys Med, 130;138-146. (2022) DOI: 10.1016/j.ejmp.2022.10.009
Radiomics software comparison using digital phantom and patient data: IBSI-compliance does not guarantee concordance of feature values
Z Paquier, SL Chao, A Acquisto, et al. Biomed Phys Eng Express, 8(6). (2022) DOI: 10.1088/2057-1976/ac8e6f
Machine learning model using F-18-FDG PET/CT-based biomarkers to support clinical decision making in advanced chemorefractory metastatic colorectal cancer.
J Dhont, H Levillain, T Guiot, et al. Eur J Nucl Med Mol Imaging, 49(1);S242-243. (2022) DOI: 10.1007/s00259-022-05924-4
Understanding the Radiobiological Mechanisms Induced by 177Lu-DOTATATE in Comparison to External Beam Radiation Therapy
Delbart, W., Karabet, J., Marin, G., et al. Int J of molecular sciences, 23(20), 12369. (2022). DOI: 10.3390/ijms232012369
Mouse genomic associations with in vitro sensitivity to simulated space radiation.
Cekanaviciute, E., Tran, D., Nguyen, H., et al. Life Sciences in Space Research, 36, 47-58. (2022). DOI: 10.1016/j.lssr.2022.07.006
International recommendations for personalized selective internal radiation therapy of primary and metastatic liver diseases with yttrium-90 resin microspheres.
Levillain H, Bagni O, Deroose CM, et al. Eur J Nucl Med Mol Imaging. 48(5):1570-1584. (2021) doi:10.1007/s00259-020-05163-5.
Combined quality and dose-volume histograms for assessing the predictive value of 99mTc-MAA SPECT/CT simulation for personalizing radioembolization treatment in liver metastatic colorectal cancer.
Levillain H, Burghelea M, Derijckere ID, et al. EJNMMI Phys. 7(1):75. (2020) doi: 10.1186/s40658-020-00345-4.
Prognostic value of a three-scale grading system based on combining molecular imaging with 68Ga-DOTATATE and 18F-FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasias.
Karfis I, Marin G, Levillain H, et al. Oncotarget. 11(6):589-599. (2020) doi: 10.18632/oncotarget.27460.
2021
Quantification of radiation-induced DNA double strand break repair foci to evaluate and predict biological responses to ionizing radiation
Penninckx, S., Pariset, E., Cekanaviciute, E., et al. NAR cancer, 3(4), zcab046. (2021). DOI: 10.1093/narcan/zcab046
Metallic Nanoparticles: A Useful Prompt Gamma Emitter for Range Monitoring in Proton Therapy?
Penninckx, S., Hespeels, F., Smeets, J., et al. Radiation, 1(4), 305-316 (2021). DOI: 10.3390/radiation1040025
Considering cell proliferation to optimize detection of radiation-induced 53BP1 positive foci in 15 mouse strains ex vivo
Penninckx, S., Pariset, E., Acuna, A. U., et al. Radiation Research, 195(1), 47-59. (2021). DOI: 10.1667/RADE-20-00165.1
2020
The metabolic clinical risk score as a new prognostic model for surgical decision-making in patients with colorectal liver metastases.
Duran Derijckere I, Levillain H, Bohlok A, et al. J Surg Oncol. 121(2):350-356. (2020) doi: 10.1002/jso.25763.
2019
Personalised radioembolization improves outcomes in refractory intra-hepatic cholangiocarcinoma: a multicenter study.
Levillain H, Duran Derijckere I, Ameye L,et al. Eur J Nucl Med Mol Imaging. 46(11):2270-2279. (2019) doi: 10.1007/s00259-019-04427-z.
2018
Selective internal radiation therapy (SIRT) before partial hepatectomy or radiofrequency destruction for treatment of hepatocellular carcinoma in cirrhotic patients: a feasibility and safety pilot study.
Lemaire M, Lucidi V, Bouazza F, et al. HPB (Oxford). 20(7):641-648. (2018) doi: 10.1016/j.hpb.2018.01.006.
A dosimetry procedure for organs-at-risk in 177Lu peptide receptor radionuclide therapy of patients with neuroendocrine tumours.
Marin G, Vanderlinden B, Karfis I, et al. Phys Med. Dec;56:41-49. (2018) doi: 10.1016/j.ejmp.2018.11.001.